5F5P
Molecular Basis for Shroom2 Recognition by Rock1
Summary for 5F5P
Entry DOI | 10.2210/pdb5f5p/pdb |
Related | 3THF 4L2W |
Descriptor | Protein Shroom2, Rho-associated protein kinase 1, CHLORIDE ION (3 entities in total) |
Functional Keywords | coiled-coil, complex, cytoskeleton, kinase, protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 138410.09 |
Authors | Zalewski, J.K.,VanDemark, A.P.,Heroux, A. (deposition date: 2015-12-04, release date: 2016-10-19, Last modification date: 2023-09-27) |
Primary citation | Zalewski, J.K.,Mo, J.H.,Heber, S.,Heroux, A.,Gardner, R.G.,Hildebrand, J.D.,VanDemark, A.P. Structure of the Shroom-Rho Kinase Complex Reveals a Binding Interface with Monomeric Shroom That Regulates Cell Morphology and Stimulates Kinase Activity. J. Biol. Chem., 291:25364-25374, 2016 Cited by PubMed: 27758857DOI: 10.1074/jbc.M116.738559 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.568 Å) |
Structure validation
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