5F4E
Crystal structure of the human sperm Izumo1 and egg Juno complex
Summary for 5F4E
| Entry DOI | 10.2210/pdb5f4e/pdb |
| Related | 5F4Q 5F4T 5F4V |
| Descriptor | Izumo sperm-egg fusion protein 1, Sperm-egg fusion protein Juno, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
| Functional Keywords | glycoprotein, membrane-bound, cysteine-rich, complex, cell adhesion |
| Biological source | Homo sapiens (Human) More |
| Cellular location | Membrane ; Single-pass type I membrane protein : Q8IYV9 Cell membrane ; Lipid-anchor, GPI-anchor : A6ND01 |
| Total number of polymer chains | 2 |
| Total formula weight | 52063.85 |
| Authors | Aydin, H.,Sultana, A.,Lee, J.E. (deposition date: 2015-12-03, release date: 2016-06-15, Last modification date: 2023-09-27) |
| Primary citation | Aydin, H.,Sultana, A.,Li, S.,Thavalingam, A.,Lee, J.E. Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex. Nature, 534:562-565, 2016 Cited by PubMed: 27309818DOI: 10.1038/nature18595 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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