5EX5
Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with 7-deaza-ADP and inorganic phosphate
Summary for 5EX5
Entry DOI | 10.2210/pdb5ex5/pdb |
Related | 5EVZ 5EXW 5EY4 5F0X 5F1X 5F2R |
Descriptor | 78 kDa glucose-regulated protein, MAGNESIUM ION, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | chaperone, atpase domain, nucleotide-binding, endoplasmic reticulum |
Biological source | Homo sapiens (Human) |
Cellular location | Endoplasmic reticulum lumen: P11021 |
Total number of polymer chains | 2 |
Total formula weight | 89803.16 |
Authors | Hughes, S.J.,Antoshchenko, T.,Song, J.H.,Pizarro, J.,Park, H.W. (deposition date: 2015-11-23, release date: 2016-06-15, Last modification date: 2023-09-27) |
Primary citation | Hughes, S.J.,Antoshchenko, T.,Chen, Y.,Lu, H.,Pizarro, J.C.,Park, H.W. Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs. Plos One, 11:e0154862-e0154862, 2016 Cited by PubMed: 27144892DOI: 10.1371/journal.pone.0154862 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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