5EV1

Structure I of Intact U2AF65 Recognizing a 3' Splice Site Signal

Summary for 5EV1

• Entry DOI: 10.2210/pdb5ev1/pdb
• Related: 5EV2 5EV3 5EV4
• Descriptor: Splicing factor U2AF 65 kDa subunit, DNA/RNA (5'-R(*UP*UP*U)-D(P*UP*UP*(BRU)P*U)-R(P*UP*U)-3'), SODIUM ION, ... (6 entities in total)
• Functional Keywords: protein-rna complex, rna splicing factor, rna recognition motif, polypyrimidine tract, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 24997.71

Authors

Agrawal, A.A.,Jenkins, J.L.,Kielkopf, C.L. (deposition date: 2015-11-19, release date: 2016-02-24, Last modification date: 2023-09-27)

• Primary citation: Agrawal, A.A.,Salsi, E.,Chatrikhi, R.,Henderson, S.,Jenkins, J.L.,Green, M.R.,Ermolenko, D.N.,Kielkopf, C.L.; An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal.; Nat Commun, 7:10950-10950, 2016; PubMed: 26952537; DOI: 10.1038/ncomms10950

Experimental method

X-RAY DIFFRACTION (2.037 Å)