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5EV1

Structure I of Intact U2AF65 Recognizing a 3' Splice Site Signal

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Splicing factor U2AF 65 kDa subunitpolymer20121970.01UniProt (P26368)
Pfam (PF00076)
Homo sapiens (Human)U2 auxiliary factor 65 kDa subunit,hU2AF65,U2 snRNP auxiliary factor large subunit
2B
(B)
DNA/RNA (5'-R(*UP*UP*U)-D(P*UP*UP*(BRU)P*U)-R(P*UP*U)-3')polymer92725.41synthetic construct
3C, F
(A, B)
SODIUM IONnon-polymer23.02Chemie (NA)
4D
(A)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
5E
(A)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
6G, H
(A, B)
waterwater18.0118Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight24695.4
Non-Polymers*Number of molecules4
Total formula weight302.3
All*Total formula weight24997.7
*Water molecules are not included.

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PDB entries from 2025-07-16

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