5EV1

Structure I of Intact U2AF65 Recognizing a 3' Splice Site Signal

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding
A	0005634	cellular_component	nucleus
A	0006397	biological_process	mRNA processing

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue NA A 401

Chain	Residue
A	ASP206
A	ASP206

---

site_id	AC2
Number of Residues	3
Details	binding site for residue PGE A 402

Chain	Residue
A	GLN172
A	VAL246
A	HOH569

---

site_id	AC3
Number of Residues	1
Details	binding site for residue PEG A 403

Chain	Residue
A	TYR245

---

site_id	AC4
Number of Residues	4
Details	binding site for residue NA B 101

Chain	Residue
B	U3
B	U2
B	U2
B	U3

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	82
Details	Domain: {"description":"RRM 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	78
Details	Domain: {"description":"RRM 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00176","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"5-hydroxylysine; by JMJD6","evidences":[{"source":"PubMed","id":"19574390","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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