5EV1
Structure I of Intact U2AF65 Recognizing a 3' Splice Site Signal
Summary for 5EV1
Entry DOI | 10.2210/pdb5ev1/pdb |
Related | 5EV2 5EV3 5EV4 |
Descriptor | Splicing factor U2AF 65 kDa subunit, DNA/RNA (5'-R(*UP*UP*U)-D(P*UP*UP*(BRU)P*U)-R(P*UP*U)-3'), SODIUM ION, ... (6 entities in total) |
Functional Keywords | protein-rna complex, rna splicing factor, rna recognition motif, polypyrimidine tract, rna binding protein-rna complex, rna binding protein/rna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 24997.71 |
Authors | Agrawal, A.A.,Jenkins, J.L.,Kielkopf, C.L. (deposition date: 2015-11-19, release date: 2016-02-24, Last modification date: 2023-09-27) |
Primary citation | Agrawal, A.A.,Salsi, E.,Chatrikhi, R.,Henderson, S.,Jenkins, J.L.,Green, M.R.,Ermolenko, D.N.,Kielkopf, C.L. An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7:10950-10950, 2016 Cited by PubMed: 26952537DOI: 10.1038/ncomms10950 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.037 Å) |
Structure validation
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