5ERX
Crystal Structure of APO MenD from M. tuberculosis - I222
Summary for 5ERX
Entry DOI | 10.2210/pdb5erx/pdb |
Related | 5ERY 5ESD 5ESO 5ESS 5ESU |
Descriptor | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase (2 entities in total) |
Functional Keywords | menaquinone biosynthesis, mend, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate synthase, thiamin-diphosphate dependent enzyme, pyruvate oxidase family, transferase |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Total number of polymer chains | 1 |
Total formula weight | 60068.94 |
Authors | Johnston, J.M.,Jirgis, E.N.M.,Bashiri, G.,Bulloch, E.M.M.,Baker, E.N. (deposition date: 2015-11-16, release date: 2016-06-22, Last modification date: 2024-03-06) |
Primary citation | Jirgis, E.N.,Bashiri, G.,Bulloch, E.M.,Johnston, J.M.,Baker, E.N. Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms. Structure, 24:1167-1177, 2016 Cited by PubMed: 27291649DOI: 10.1016/j.str.2016.04.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.729 Å) |
Structure validation
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