5EMN
Crystal Structure of Human NADPH-Cytochrome P450 Reductase(A287P mutant)
Summary for 5EMN
Entry DOI | 10.2210/pdb5emn/pdb |
Related | 3QE2 |
Descriptor | NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total) |
Functional Keywords | human cypor, abs-like phenotype, flavoprotein, cytochrome p450 reductase, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 144282.61 |
Authors | Xia, C.,Marohnic, C.,Panda, S.,Masters, B.S.,Kim, J.J.K. (deposition date: 2015-11-06, release date: 2016-08-17, Last modification date: 2023-09-27) |
Primary citation | McCammon, K.M.,Panda, S.P.,Xia, C.,Kim, J.J.,Moutinho, D.,Kranendonk, M.,Auchus, R.J.,Lafer, E.M.,Ghosh, D.,Martasek, P.,Kar, R.,Masters, B.S.,Roman, L.J. Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype. J.Biol.Chem., 291:20487-20502, 2016 Cited by PubMed: 27496950DOI: 10.1074/jbc.M116.716019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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