5ELV

Crystal structure of the GluA2 ligand-binding domain (S1S2J-L504-N775) in complex with glutamate and BPAM-521 at 1.92 A resolution

Summary for 5ELV

Entry DOI	10.2210/pdb5elv/pdb
Related	3IL1 3TDJ 3TDK 4N07 4U4S 4U4X
Descriptor	Glutamate receptor 2,Glutamate receptor 2, SULFATE ION, GLYCEROL, ... (9 entities in total)
Functional Keywords	ampa receptor ligand-binding domain, bpam-521 allosteric modulation, membrane protein, fusion protein
Biological source	Rattus norvegicus (Rat) More
Cellular location	Cell membrane ; Multi-pass membrane protein : P19491
Total number of polymer chains	2
Total formula weight	60980.90
Authors	Krintel, C.,Juknaite, L.,Frydenvang, K.,Kastrup, J.S. (deposition date: 2015-11-05, release date: 2016-05-04, Last modification date: 2024-01-10)
Primary citation	Krintel, C.,Francotte, P.,Pickering, D.S.,Juknaite, L.,Phlsgaard, J.,Olsen, L.,Frydenvang, K.,Goffin, E.,Pirotte, B.,Kastrup, J.S. Enthalpy-Entropy Compensation in the Binding of Modulators at Ionotropic Glutamate Receptor GluA2. Biophys.J., 110:2397-2406, 2016 Cited by PubMed: 27276258 DOI: 10.1016/j.bpj.2016.04.032 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.92 Å)

Structure validation