5EIX

QUINOLONE-STABILIZED CLEAVAGE COMPLEX OF TOPOISOMERASE IV FROM KLEBSIELLA PNEUMONIAE

Summary for 5EIX

Entry DOI	10.2210/pdb5eix/pdb
Related	3LTN 3RAD 3RAE 3RAF 4I3H
Descriptor	DNA topoisomerase 4 subunit B,DNA topoisomerase 4 subunit A, SYMMETRISED E-SITE (PRE-CUT), MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	klebsiella pneumoniae, cleavage complex, quinolone, levofloxacin, topoisomerase iv, dna binding, isomerase, isomerase-dna complex, isomerase/dna
Biological source	Klebsiella pneumoniae More
Cellular location	Cell membrane ; Peripheral membrane protein : R4YE07
Total number of polymer chains	12
Total formula weight	361652.64
Authors	Veselkov, D.A.,Laponogov, I.,Pan, X.-S.,Selvarajah, J.,Branstrom, A.,Fisher, L.M.,Sanderson, M.R. (deposition date: 2015-10-30, release date: 2016-04-13, Last modification date: 2017-08-30)
Primary citation	Veselkov, D.A.,Laponogov, I.,Pan, X.S.,Selvarajah, J.,Skamrova, G.B.,Branstrom, A.,Narasimhan, J.,Prasad, J.V.,Fisher, L.M.,Sanderson, M.R. Structure of a quinolone-stabilized cleavage complex of topoisomerase IV from Klebsiella pneumoniae and comparison with a related Streptococcus pneumoniae complex. Acta Crystallogr D Struct Biol, 72:488-496, 2016 Cited by PubMed: 27050128 DOI: 10.1107/S2059798316001212 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.35 Å)

Structure validation