5EIX

QUINOLONE-STABILIZED CLEAVAGE COMPLEX OF TOPOISOMERASE IV FROM KLEBSIELLA PNEUMONIAE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
A	0005524	molecular_function	ATP binding
A	0005694	cellular_component	chromosome
A	0006259	biological_process	DNA metabolic process
A	0006265	biological_process	DNA topological change
B	0003677	molecular_function	DNA binding
B	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
B	0005524	molecular_function	ATP binding
B	0005694	cellular_component	chromosome
B	0006259	biological_process	DNA metabolic process
B	0006265	biological_process	DNA topological change
G	0003677	molecular_function	DNA binding
G	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
G	0005524	molecular_function	ATP binding
G	0005694	cellular_component	chromosome
G	0006259	biological_process	DNA metabolic process
G	0006265	biological_process	DNA topological change
J	0003677	molecular_function	DNA binding
J	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
J	0005524	molecular_function	ATP binding
J	0005694	cellular_component	chromosome
J	0006259	biological_process	DNA metabolic process
J	0006265	biological_process	DNA topological change

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue MG A 1501

Chain	Residue
A	ASP491
A	ASP493

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site_id	AC2
Number of Residues	1
Details	binding site for residue MG A 1502

Chain	Residue
F	LFX100

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site_id	AC3
Number of Residues	7
Details	binding site for residue LFX F 100

Chain	Residue
I	DG1
A	LYS442
A	SER1080
A	MG1502
E	DT15
F	DC4
F	DA5

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site_id	AC4
Number of Residues	2
Details	binding site for residue MG B 1501

Chain	Residue
B	ASP491
B	ASP493

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site_id	AC5
Number of Residues	6
Details	binding site for residue LFX D 100

Chain	Residue
B	SER1080
C	DT15
D	DC4
D	DA5
L	DG1
L	MG101

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site_id	AC6
Number of Residues	2
Details	binding site for residue MG G 1501

Chain	Residue
G	ASP491
G	ASP493

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site_id	AC7
Number of Residues	1
Details	binding site for residue MG G 1502

Chain	Residue
I	LFX100

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site_id	AC8
Number of Residues	6
Details	binding site for residue LFX I 100

Chain	Residue
F	DG1
G	SER1080
G	MG1502
H	DT15
I	DC4
I	DA5

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site_id	AC9
Number of Residues	2
Details	binding site for residue MG J 1501

Chain	Residue
J	ASP491
J	ASP493

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site_id	AD1
Number of Residues	1
Details	binding site for residue MG L 101

Chain	Residue
D	LFX100

---

site_id	AD2
Number of Residues	1
Details	binding site for residue MG L 102

Chain	Residue
L	LFX103

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site_id	AD3
Number of Residues	6
Details	binding site for residue LFX L 103

Chain	Residue
D	DG1
J	SER1080
K	DT15
L	DC4
L	DA5
L	MG102

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Functional Information from PROSITE/UniProt

site_id	PS00177
Number of Residues	9
Details	TOPOISOMERASE_II DNA topoisomerase II signature. LVEGDSAGG

Chain	Residue	Details
A	LEU417-GLY425

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