5EG4
BOVINE TRYPSIN IN COMPLEX WITH CYCLIC INHIBITOR
Summary for 5EG4
Entry DOI | 10.2210/pdb5eg4/pdb |
Related | 4MTB |
Descriptor | Cationic trypsin, CALCIUM ION, SULFATE ION, ... (6 entities in total) |
Functional Keywords | metal-binding, digestion, hydrolase-hydrolase inhibitor complex, hydrolase |
Biological source | Bos taurus (Bovine) |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 1 |
Total formula weight | 24348.49 |
Authors | Knoerlein, A.,Wagner, S.,Heine, A.,Steinmetzer, T.,Klebe, G. (deposition date: 2015-10-26, release date: 2016-07-13, Last modification date: 2024-01-10) |
Primary citation | Hinkes, S.,Wuttke, A.,Saupe, S.M.,Ivanova, T.,Wagner, S.,Knorlein, A.,Heine, A.,Klebe, G.,Steinmetzer, T. Optimization of Cyclic Plasmin Inhibitors: From Benzamidines to Benzylamines. J.Med.Chem., 59:6370-6386, 2016 Cited by PubMed: 27280436DOI: 10.1021/acs.jmedchem.6b00606 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.32 Å) |
Structure validation
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