Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004175 | molecular_function | endopeptidase activity |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005576 | cellular_component | extracellular region |
A | 0005615 | cellular_component | extracellular space |
A | 0006508 | biological_process | proteolysis |
A | 0007586 | biological_process | digestion |
A | 0008236 | molecular_function | serine-type peptidase activity |
A | 0046872 | molecular_function | metal ion binding |
A | 0097180 | cellular_component | serine protease inhibitor complex |
A | 0097655 | molecular_function | serpin family protein binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | binding site for residue CA A 501 |
Chain | Residue |
A | GLU70 |
A | ASN72 |
A | VAL75 |
A | GLU80 |
A | HOH608 |
A | HOH700 |
site_id | AC2 |
Number of Residues | 7 |
Details | binding site for residue SO4 A 502 |
Chain | Residue |
A | LYS109 |
A | HOH614 |
A | HOH679 |
A | HOH731 |
A | ASN95 |
A | THR98 |
A | ASN100 |
site_id | AC3 |
Number of Residues | 3 |
Details | binding site for residue ACT A 503 |
Chain | Residue |
A | ASP153 |
A | VAL154 |
A | LYS156 |
site_id | AC4 |
Number of Residues | 24 |
Details | binding site for residue 5N7 A 504 |
Chain | Residue |
A | HIS57 |
A | SER96 |
A | ASN97 |
A | LEU99 |
A | ASP189 |
A | SER190 |
A | CYS191 |
A | SER195 |
A | SER214 |
A | TRP215 |
A | GLY216 |
A | SER217 |
A | GLY219 |
A | CYS220 |
A | GLY226 |
A | VAL235 |
A | LYS239 |
A | GLN240 |
A | HOH625 |
A | HOH635 |
A | HOH658 |
A | HOH677 |
A | HOH715 |
A | HOH725 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
Chain | Residue | Details |
A | VAL53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
Chain | Residue | Details |
A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
A | HIS57 | |
A | ASP102 | |
A | SER195 | |
site_id | SWS_FT_FI2 |
Number of Residues | 7 |
Details | BINDING: |
Chain | Residue | Details |
A | GLU70 | |
A | ASN72 | |
A | VAL75 | |
A | GLU80 | |
A | ASP189 | |
A | GLN192 | |
A | SER195 | |