5E7D

Crystal Structure of the fifth bromodomain of human PB1 in complex with a hydroxyphenyl ligand

5E7D の概要

• エントリーDOI: 10.2210/pdb5e7d/pdb
• 分子名称: Protein polybromo-1, (2E)-3-(dimethylamino)-1-(2-hydroxyphenyl)prop-2-en-1-one, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: bromodomain, chemical probe, ligand, inhibitor, structural genomics consortium, sgc, transcription
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Nucleus: Q86U86
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 59418.97

構造登録者

Filippakopoulos, P.,Picaud, S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Owen, D.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2015-10-12, 公開日: 2016-10-12, 最終更新日: 2024-05-08)

• 主引用文献: Filippakopoulos, P.,Picaud, S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Owen, D.,Knapp, S.; Crystal Structure of the fifth bromodomain of human PB1 in complex with a hydroxyphenyl ligand; To Be Published,

実験手法

X-RAY DIFFRACTION (1.87 Å)