Crystal structure of the archaeal tRNA m2G/m22G10 methyltransferase (aTrm11) in complex with S-adenosyl-L-methionine (SAM) from Thermococcus kodakarensis

Summary for 5E72

DescriptorN2, N2-dimethylguanosine tRNA methyltransferase, S-ADENOSYLMETHIONINE (3 entities in total)
Functional Keywordstrna methyltransferase, sam, transferase
Biological sourceThermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Total number of polymer chains1
Total molecular weight39698.57
Hirata, A. (deposition date: 2015-10-11, release date: 2016-07-06, Last modification date: 2020-02-19)
Primary citation
Hirata, A.,Nishiyama, S.,Tamura, T.,Yamauchi, A.,Hori, H.
Structural and functional analyses of the archaeal tRNA m2G/m22G10 methyltransferase aTrm11 provide mechanistic insights into site specificity of a tRNA methyltransferase that contains common RNA-binding modules.
Nucleic Acids Res., 2016
PubMed: 27325738 (PDB entries with the same primary citation)
DOI: 10.1093/nar/gkw561
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.22450 0.7% 4.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-09-16