5E72

Crystal structure of the archaeal tRNA m2G/m22G10 methyltransferase (aTrm11) in complex with S-adenosyl-L-methionine (SAM) from Thermococcus kodakarensis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	N2, N2-dimethylguanosine tRNA methyltransferase	polymer	346	39300.1	1	UniProt (Q5JID5) Pfam (PF02926) Pfam (PF01170) In PDB	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
2	A	S-ADENOSYLMETHIONINE	non-polymer		398.4	1	Chemie (SAM)
3		water	water		18.0	282	Chemie (HOH)

Sequence modifications

A: 1 - 331 (UniProt: Q5JID5)

PDB	External Database	Details
Leu 332	-	expression tag
Glu 333	-	expression tag
Val 334	-	expression tag
Leu 335	-	expression tag
Phe 336	-	expression tag
Gln 337	-	expression tag
Gly 338	-	expression tag
Pro 339	-	expression tag
Ser 340	-	expression tag
His 341	-	expression tag
His 342	-	expression tag
His 343	-	expression tag
His 344	-	expression tag
His 345	-	expression tag
His 346	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	39300.1
Non-Polymers*	Number of molecules	1
	Total formula weight	398.4
All*	Total formula weight	39698.6

*Water molecules are not included.