5E4R

Crystal structure of domain-duplicated synthetic class II ketol-acid reductoisomerase 2Ia_KARI-DD

Summary for 5E4R

• Entry DOI: 10.2210/pdb5e4r/pdb
• Descriptor: Ketol-acid reductoisomerase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, MAGNESIUM ION, ... (7 entities in total)
• Functional Keywords: ketol-acid reductiosomerase, protein knot, psuedodimer, protein engineering, chimera protein, oxidoreductase
• Biological source: Ignisphaera aggregans (strain DSM 17230 / JCM 13409 / AQ1.S1); More
• Total number of polymer chains: 1
• Total formula weight: 56339.24

Authors

Cahn, J.K.B.,Brinkmann-Chen, S.,Buller, A.R.,Arnold, F.H. (deposition date: 2015-10-07, release date: 2015-12-23, Last modification date: 2023-09-27)

• Primary citation: Cahn, J.K.,Brinkmann-Chen, S.,Buller, A.R.,Arnold, F.H.; Artificial domain duplication replicates evolutionary history of ketol-acid reductoisomerases.; Protein Sci., 25:1241-1248, 2016; PubMed: 26644020; DOI: 10.1002/pro.2852

Experimental method

X-RAY DIFFRACTION (1.94 Å)