5E4R
Crystal structure of domain-duplicated synthetic class II ketol-acid reductoisomerase 2Ia_KARI-DD
Summary for 5E4R
Entry DOI | 10.2210/pdb5e4r/pdb |
Descriptor | Ketol-acid reductoisomerase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, MAGNESIUM ION, ... (7 entities in total) |
Functional Keywords | ketol-acid reductiosomerase, protein knot, psuedodimer, protein engineering, chimera protein, oxidoreductase |
Biological source | Ignisphaera aggregans (strain DSM 17230 / JCM 13409 / AQ1.S1) More |
Total number of polymer chains | 1 |
Total formula weight | 56339.24 |
Authors | Cahn, J.K.B.,Brinkmann-Chen, S.,Buller, A.R.,Arnold, F.H. (deposition date: 2015-10-07, release date: 2015-12-23, Last modification date: 2023-09-27) |
Primary citation | Cahn, J.K.,Brinkmann-Chen, S.,Buller, A.R.,Arnold, F.H. Artificial domain duplication replicates evolutionary history of ketol-acid reductoisomerases. Protein Sci., 25:1241-1248, 2016 Cited by PubMed: 26644020DOI: 10.1002/pro.2852 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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