5E3H

Structural Basis for RNA Recognition and Activation of RIG-I

「3TMI」から置き換えられました

5E3H の概要

• エントリーDOI: 10.2210/pdb5e3h/pdb
• 関連するPDBエントリー: 3TMI
• 分子名称: Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3'), ZINC ION, ... (7 entities in total)
• 機能のキーワード: adenosine triphosphatases, adenosine triphosphate, dead-box rna helicases, enzyme activation, fluorometry, humans, immunity, innate, models, molecular, nucleic acid conformation, pliability, protein binding, protein structure, tertiary, proteolysis, rna, double-stranded, rna-binding proteins, scattering, small angle, structure-activity relationship, substrate specificity, trypsin, hydrolase, hydrolase-rna complex, hydrolase/rna
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 89273.81

構造登録者

Jiang, F.,Miller, M.T.,Marcotrigiano, J. (登録日: 2015-10-02, 公開日: 2015-11-18, 最終更新日: 2023-09-27)

• 主引用文献: Jiang, F.,Ramanathan, A.,Miller, M.T.,Tang, G.Q.,Gale, M.,Patel, S.S.,Marcotrigiano, J.; Structural basis of RNA recognition and activation by innate immune receptor RIG-I.; Nature, 479:423-427, 2011; PubMed: 21947008; DOI: 10.1038/nature10537

実験手法

X-RAY DIFFRACTION (2.7 Å)