5E3C

Structure of human DPP3 in complex with hemorphin like opioid peptide IVYPW

Summary for 5E3C

• Entry DOI: 10.2210/pdb5e3c/pdb
• Related: 3FVY 3T6B
• Descriptor: Dipeptidyl peptidase 3, IVYPW, ZINC ION, ... (6 entities in total)
• Functional Keywords: opioid-peptide, zinc-hydrolase, peptidase, inhibitor complex, hydrolase
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm, cytosol : Q9NY33
• Total number of polymer chains: 2
• Total formula weight: 82378.61

Authors

Kumar, P.,Reithofer, V.,Reisinger, M.,Pavkov-Keller, T.,Wallner, S.,Macheroux, P.,Gruber, K. (deposition date: 2015-10-02, release date: 2016-04-13, Last modification date: 2024-01-10)

• Primary citation: Kumar, P.,Reithofer, V.,Reisinger, M.,Wallner, S.,Pavkov-Keller, T.,Macheroux, P.,Gruber, K.; Substrate complexes of human dipeptidyl peptidase III reveal the mechanism of enzyme inhibition.; Sci Rep, 6:23787-23787, 2016; PubMed: 27025154; DOI: 10.1038/srep23787

Experimental method

X-RAY DIFFRACTION (2.765 Å)