5E3C
Structure of human DPP3 in complex with hemorphin like opioid peptide IVYPW
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dipeptidyl peptidase 3 | polymer | 726 | 81548.7 | 1 | UniProt (Q9NY33) Pfam (PF03571) In PDB | Homo sapiens (Human) | Dipeptidyl aminopeptidase III,Dipeptidyl arylamidase III,Dipeptidyl peptidase III,DPP III,Enkephalinase B |
| 2 | B | IVYPW | polymer | 5 | 676.8 | 1 | Homo sapiens | ||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | A | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 6 | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A: 1 - 726 (UniProt: Q9NY33)
| PDB | External Database | Details |
|---|---|---|
| Ser 19 | Cys 19 | engineered mutation |
| Cys 207 | Glu 207 | engineered mutation |
| Ala 451 | Glu 451 | engineered mutation |
| Cys 491 | Ser 491 | engineered mutation |
| Ser 519 | Cys 519 | engineered mutation |
| Ser 654 | Cys 654 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82225.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 153.1 | |
| All* | Total formula weight | 82378.6 |
