5E2L

3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis in complex with D-phenylalanine

Summary for 5E2L

• Entry DOI: 10.2210/pdb5e2l/pdb
• Related: 2YPO 2YPP 2YPQ 3KGF 3NUD 3NUE 3NV8 3RZI 5E40 5E4N
• Descriptor: 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase, SULFATE ION, MANGANESE (II) ION, ... (7 entities in total)
• Functional Keywords: 3-deoxy-7-phosphoheptulosonate synthase, allosteric regulation, allosteric site, amino acid, transferase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 2
• Total formula weight: 102938.81

Authors

Reichau, S.,Jiao, W.,Parker, E.J. (deposition date: 2015-10-01, release date: 2016-06-01, Last modification date: 2023-09-27)

• Primary citation: Reichau, S.,Blackmore, N.J.,Jiao, W.,Parker, E.J.; Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis Using -Amino Acids.; Plos One, 11:e0152723-e0152723, 2016; PubMed: 27128682; DOI: 10.1371/journal.pone.0152723

Experimental method

X-RAY DIFFRACTION (2.5 Å)