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5E2L

3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis in complex with D-phenylalanine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
3-deoxy-D-arabinoheptulosonate-7-phosphate synthasepolymer46450828.42UniProt (A0A0E8NFD1)
Pfam (PF01474)
UniProt (by SIFTS) (O53512)
Mycobacterium tuberculosis
2C, J, K, L, M
(A, B)
SULFATE IONnon-polymer96.15Chemie (SO4)
3D, N
(A, B)
MANGANESE (II) IONnon-polymer54.92Chemie (MN)
4E, G, H, O, Q
(A, B)
CHLORIDE IONnon-polymer35.55Chemie (CL)
5F, P
(A, B)
GLYCEROLnon-polymer92.12Chemie (GOL)
6I, R
(A, B)
D-PHENYLALANINEnon-polymer165.22Chemie (DPN)
7S, T
(A, B)
waterwater18.082Chemie (HOH)
Sequence modifications
A, B: 1 - 462 (UniProt: A0A0E8NFD1)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight101656.8
Non-Polymers*Number of molecules16
Total formula weight1282.0
All*Total formula weight102938.8
*Water molecules are not included.

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PDB entries from 2025-07-23

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