5E0V
Human PCNA variant (S228I) complexed with FEN1 at 2.1 Angstroms
Summary for 5E0V
Entry DOI | 10.2210/pdb5e0v/pdb |
Related | 1AXC 5E0T 5E0U |
Descriptor | Proliferating cell nuclear antigen, Flap endonuclease 1 (3 entities in total) |
Functional Keywords | dna replication, sliding clamp, dna binding protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : P12004 Mitochondrion . Nucleus, nucleolus : B4DWZ4 |
Total number of polymer chains | 4 |
Total formula weight | 61189.57 |
Authors | Duffy, C.M.,Hilbert, B.J.,Kelch, B.A. (deposition date: 2015-09-29, release date: 2016-04-20, Last modification date: 2023-09-27) |
Primary citation | Duffy, C.M.,Hilbert, B.J.,Kelch, B.A. A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site. J.Mol.Biol., 428:1023-1040, 2016 Cited by PubMed: 26688547DOI: 10.1016/j.jmb.2015.11.029 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.074 Å) |
Structure validation
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