5E0K

X-ray crystal structure of tryptophan synthase complex from Pyrococcus furiosus at 2.76 A

Summary for 5E0K

• Entry DOI: 10.2210/pdb5e0k/pdb
• Related: 5DVZ 5DW0 5DW3
• Descriptor: Tryptophan synthase alpha chain, Tryptophan synthase beta chain 1, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: complex, plp, lyase, enzyme
• Biological source: Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1); More
• Total number of polymer chains: 12
• Total formula weight: 429095.17

Authors

Buller, A.R.,Murciano-Calles, J.,Arnold, F.H. (deposition date: 2015-09-29, release date: 2015-11-11, Last modification date: 2019-12-25)

• Primary citation: Buller, A.R.,Brinkmann-Chen, S.,Romney, D.K.,Herger, M.,Murciano-Calles, J.,Arnold, F.H.; Directed evolution of the tryptophan synthase beta-subunit for stand-alone function recapitulates allosteric activation.; Proc.Natl.Acad.Sci.USA, 112:14599-14604, 2015; PubMed: 26553994; DOI: 10.1073/pnas.1516401112

Experimental method

X-RAY DIFFRACTION (2.76 Å)