5E0K

X-ray crystal structure of tryptophan synthase complex from Pyrococcus furiosus at 2.76 A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (A, C, E, G, I...)	Tryptophan synthase alpha chain	polymer	248	27535.8	6	UniProt (Q8U094) Pfam (PF00290)	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
2	B, D, F, H, J... (B, D, F, H, J...)	Tryptophan synthase beta chain 1	polymer	396	43885.0	6	UniProt (Q8U093) Pfam (PF00291)	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
3	M, N, O, P, Q... (B, D, F, H, J...)	PHOSPHATE ION	non-polymer		95.0	6	Chemie (PO4)
4	AA, BA, CA, DA, S... (I, J, K, L, A...)	water	water		18.0	73	Chemie (HOH)

Sequence modifications

B, D, F, H, J, L: 1 - 388 (UniProt: Q8U093)

PDB	External Database	Details
Leu 389	-	expression tag
Glu 390	-	expression tag
His 391	-	expression tag
His 392	-	expression tag
His 393	-	expression tag
His 394	-	expression tag
His 395	-	expression tag
His 396	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	428525.3
Non-Polymers*	Number of molecules	6
	Total formula weight	569.8
All*	Total formula weight	429095.2

*Water molecules are not included.