5DO9
Structure of regulator of G protein signaling 8 (RGS8) in complex with AlF4-activated Galpha-q
Summary for 5DO9
Entry DOI | 10.2210/pdb5do9/pdb |
Descriptor | Guanine nucleotide-binding protein G(q) subunit alpha, Regulator of G-protein signaling 8, GUANOSINE-5'-DIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | gtp-binding protein alpha subunits, gq-g11, rgs proteins, protein binding |
Biological source | Mus musculus (Mouse) More |
Cellular location | Nucleus : P21279 Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : P57771 |
Total number of polymer chains | 6 |
Total formula weight | 159555.84 |
Authors | Taylor, V.G.,Tesmer, J.J.G. (deposition date: 2015-09-10, release date: 2016-01-20, Last modification date: 2024-03-06) |
Primary citation | Taylor, V.G.,Bommarito, P.A.,Tesmer, J.J. Structure of the Regulator of G Protein Signaling 8 (RGS8)-G alpha q Complex: MOLECULAR BASIS FOR G alpha SELECTIVITY. J.Biol.Chem., 291:5138-5145, 2016 Cited by PubMed: 26755720DOI: 10.1074/jbc.M115.712075 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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