5DO9
Structure of regulator of G protein signaling 8 (RGS8) in complex with AlF4-activated Galpha-q
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 314 | 36853.9 | 3 | UniProt (P21279) Pfam (PF00503) | Mus musculus (Mouse) | Guanine nucleotide-binding protein alpha-q |
| 2 | B, D, F (B, D, F) | Regulator of G-protein signaling 8 | polymer | 134 | 15760.9 | 3 | UniProt (P57771) Pfam (PF00615) | Homo sapiens (Human) | RGS8 |
| 3 | G, J, M (A, C, E) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 3 | Chemie (GDP) | |||
| 4 | H, K, N (A, C, E) | TETRAFLUOROALUMINATE ION | non-polymer | 103.0 | 3 | Chemie (ALF) | |||
| 5 | I, L, O (A, C, E) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 6 | P, Q, R, S, T... (A, B, C, D, E...) | water | water | 18.0 | 231 | Chemie (HOH) |
Sequence modifications
B, D, F: 42 - 173 (UniProt: P57771)
| PDB | External Database | Details |
|---|---|---|
| Ser 40 | - | expression tag |
| Met 41 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 157844.4 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1711.4 | |
| All* | Total formula weight | 159555.8 |
