5DO9
Structure of regulator of G protein signaling 8 (RGS8) in complex with AlF4-activated Galpha-q
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 314 | 36853.9 | 3 | UniProt (P21279) Pfam (PF00503) | Mus musculus (Mouse) | Guanine nucleotide-binding protein alpha-q |
| 2 | B, D, F (B, D, F) | Regulator of G-protein signaling 8 | polymer | 134 | 15760.9 | 3 | UniProt (P57771) Pfam (PF00615) | Homo sapiens (Human) | RGS8 |
| 3 | G, J, M (A, C, E) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 3 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 4 | H, K, N (A, C, E) | TETRAFLUOROALUMINATE ION | non-polymer | 103.0 | 3 | Chemie (ALF) PubChem (5311325) | |||
| 5 | I, L, O (A, C, E) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) PubChem (888) | |||
| 6 | P, Q, R, S, T... (A, B, C, D, E...) | water | water | 18.0 | 231 | Chemie (HOH) |
Sequence modifications
B, D, F: 42 - 173 (UniProt: P57771)
| PDB | External Database | Details |
|---|---|---|
| Ser 40 | - | expression tag |
| Met 41 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 157844.4 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1711.4 | |
| All* | Total formula weight | 159555.8 |
