5DMK
Crystal Structure of IAg7 in complex with RLGL-WE14
Summary for 5DMK
Entry DOI | 10.2210/pdb5dmk/pdb |
Descriptor | H-2 class II histocompatibility antigen, A-D alpha chain, beta chain of Major Histocompatibility Complex Class II, I-Ag7,H2-Ab1 protein, CITRATE ANION, ... (4 entities in total) |
Functional Keywords | chromogranin a, type i diabetes, t cell, fusion protein, immune system |
Biological source | Mus musculus More |
Cellular location | Membrane ; Single-pass type I membrane protein : P04228 |
Total number of polymer chains | 8 |
Total formula weight | 178717.80 |
Authors | Wang, Y.,Jin, N.,Dai, S.,Kappler, J.W. (deposition date: 2015-09-08, release date: 2015-10-28, Last modification date: 2016-04-06) |
Primary citation | Jin, N.,Wang, Y.,Crawford, F.,White, J.,Marrack, P.,Dai, S.,Kappler, J.W. N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes. Proc.Natl.Acad.Sci.USA, 112:13318-13323, 2015 Cited by PubMed: 26453556DOI: 10.1073/pnas.1517862112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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