5DKD
Crystal structure of the bromodomain of human BRG1 (SMARCA4) in complex with PFI-3 chemical probe
Summary for 5DKD
Entry DOI | 10.2210/pdb5dkd/pdb |
Descriptor | Transcription activator BRG1, ZINC ION, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | swi-snf complex, chromatin remodeling, brg associated factors (baf), transcription, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : P51532 |
Total number of polymer chains | 2 |
Total formula weight | 29606.87 |
Authors | Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Fedorov, O.,Savitsky, P.,Nunez-Alonso, G.,Newman, J.A.,Filippakopoulos, P.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Muller, S.,Knapp, S. (deposition date: 2015-09-03, release date: 2015-10-14, Last modification date: 2024-01-10) |
Primary citation | Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Fedorov, O.,Savitsky, P.,Nunez-Alonso, G.,Newman, J.A.,Filippakopoulos, P.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Muller, S.,Knapp, S. Crystal structure of the bromodomain of human BRG1 (SMARCA4) in complex with PFI-3 chemical probe To Be Published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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