5DBX

Crystal structure of murine SPAK(T243D) in complex with AMPPNP

Summary for 5DBX

Entry DOI	10.2210/pdb5dbx/pdb
Descriptor	STE20/SPS1-related proline-alanine-rich protein kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	kinase, transferase
Biological source	Mus musculus (Mouse)
Cellular location	Cytoplasm : Q9Z1W9
Total number of polymer chains	2
Total formula weight	75570.66
Authors	Juang, Y.-C. (deposition date: 2015-08-22, release date: 2015-09-23, Last modification date: 2023-09-27)
Primary citation	Taylor, C.A.,Juang, Y.C.,Earnest, S.,Sengupta, S.,Goldsmith, E.J.,Cobb, M.H. Domain-Swapping Switch Point in Ste20 Protein Kinase SPAK. Biochemistry, 54:5063-5071, 2015 Cited by PubMed: 26208601 DOI: 10.1021/acs.biochem.5b00593 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation