5D0R
Crystal structure of human soluble Adenylyl Cyclase with the inhibitor bithionol
Summary for 5D0R
Entry DOI | 10.2210/pdb5d0r/pdb |
Related | 4CLF 4CLK 4CLL 4CLP 4CLS 4CLT 4CLU 4CLW 4CLY 4CLZ 4CM2 |
Descriptor | Adenylate cyclase type 10, 2,2'-sulfanediylbis(4,6-dichlorophenol), ACETATE ION, ... (7 entities in total) |
Functional Keywords | lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 55475.76 |
Authors | Kleinboelting, S.,Steegborn, C. (deposition date: 2015-08-03, release date: 2016-03-16, Last modification date: 2024-01-10) |
Primary citation | Kleinboelting, S.,Ramos-Espiritu, L.,Buck, H.,Colis, L.,van den Heuvel, J.,Glickman, J.F.,Levin, L.R.,Buck, J.,Steegborn, C. Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator Site. J.Biol.Chem., 291:9776-9784, 2016 Cited by PubMed: 26961873DOI: 10.1074/jbc.M115.708255 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.24 Å) |
Structure validation
Download full validation report