5D0R
Crystal structure of human soluble Adenylyl Cyclase with the inhibitor bithionol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Adenylate cyclase type 10 | polymer | 475 | 54269.7 | 1 | UniProt (Q96PN6) Pfam (PF00211) | Homo sapiens (Human) | AH-related protein,Adenylate cyclase homolog,Germ cell soluble adenylyl cyclase,sAC,Testicular soluble adenylyl cyclase |
| 2 | B (A) | 2,2'-sulfanediylbis(4,6-dichlorophenol) | non-polymer | 356.1 | 1 | Chemie (B1T) | |||
| 3 | C (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 4 | D, E, F, G, H... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 5 | J, K, L (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 6 | M, N (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | O (A) | water | water | 18.0 | 214 | Chemie (HOH) |
Sequence modifications
A: 1 - 469 (UniProt: Q96PN6)
| PDB | External Database | Details |
|---|---|---|
| His 470 | - | expression tag |
| His 471 | - | expression tag |
| His 472 | - | expression tag |
| His 473 | - | expression tag |
| His 474 | - | expression tag |
| His 475 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 54269.7 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1206.1 | |
| All* | Total formula weight | 55475.8 |
