5CWR
Crystal Structure of human DNA polymerase lambda L431A mutant in complex with a one nucleotide DNA gap and dCTP
Summary for 5CWR
Entry DOI | 10.2210/pdb5cwr/pdb |
Related | 5CB1 |
Descriptor | DNA polymerase lambda, DNA (5'-D(*CP*GP*GP*CP*GP*GP*TP*AP*CP*TP*G)-3'), DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ... (7 entities in total) |
Functional Keywords | polymerase lambda, transferase, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: Q9UGP5 |
Total number of polymer chains | 8 |
Total formula weight | 86860.35 |
Authors | Liu, M.S.,Tsai, M.D. (deposition date: 2015-07-28, release date: 2016-02-24, Last modification date: 2023-11-08) |
Primary citation | Liu, M.S.,Tsai, H.Y.,Liu, X.X.,Ho, M.C.,Wu, W.J.,Tsai, M.D. Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda J.Am.Chem.Soc., 138:2389-2398, 2016 Cited by PubMed: 26836966DOI: 10.1021/jacs.5b13368 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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