5CU5

Crystal structure of ERAP2 without catalytic Zn(II) atom

Summary for 5CU5

Entry DOI	10.2210/pdb5cu5/pdb
Descriptor	Endoplasmic reticulum aminopeptidase 2, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	hydrolase, aminopeptidase, endoplasmic reticulum, thermolysin-like catalytic domain
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	227235.80
Authors	Saridakis, E.,Mathioudakis, N.,Giastas, P.,Mavridis, I.M.,Stratikos, E. (deposition date: 2015-07-24, release date: 2015-09-23, Last modification date: 2024-01-10)
Primary citation	Mpakali, A.,Giastas, P.,Mathioudakis, N.,Mavridis, I.M.,Saridakis, E.,Stratikos, E. Structural Basis for Antigenic Peptide Recognition and Processing by Endoplasmic Reticulum (ER) Aminopeptidase 2. J.Biol.Chem., 290:26021-26032, 2015 Cited by PubMed: 26381406 DOI: 10.1074/jbc.M115.685909 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.02 Å)

Structure validation