5CU5
Crystal structure of ERAP2 without catalytic Zn(II) atom
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Endoplasmic reticulum aminopeptidase 2 | polymer | 967 | 111530.5 | 2 | UniProt (Q6P179) Pfam (PF17900) Pfam (PF01433) Pfam (PF11838) | Homo sapiens (Human) | Leukocyte-derived arginine aminopeptidase,L-RAP |
| 2 | C (C) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
| 3 | D, F (D, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | E (E) | alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81874LD) | |||
| 5 | G, H, I, J, K... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
| 6 | P, Q (A, B) | water | water | 18.0 | 193 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 960 (UniProt: Q6P179)
| PDB | External Database | Details |
|---|---|---|
| Val 2 | Phe 2 | conflict |
| Arg 961 | - | expression tag |
| His 962 | - | expression tag |
| His 963 | - | expression tag |
| His 964 | - | expression tag |
| His 965 | - | expression tag |
| His 966 | - | expression tag |
| His 967 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 223060.9 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2184.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1990.9 | |
| All* | Total formula weight | 227235.8 |
