5CKX

Non-covalent complex of DAHP synthase and chorismate mutase from Mycobacterium tuberculosis with bound transition state analog and feedback effectors tyrosine and phenylalanine

5CKX の概要

• エントリーDOI: 10.2210/pdb5ckx/pdb
• 分子名称: Phospho-2-dehydro-3-deoxyheptonate aldolase AroG, Intracellular chorismate mutase, MANGANESE (II) ION, ... (10 entities in total)
• 機能のキーワード: protein complex, shikimate pathway, dahp-synthase, chorismate mutase, transferase-isomerase complex, transferase/isomerase
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); 詳細
• 細胞内の位置: Cytoplasm : P9WIC1
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 126411.89

構造登録者

Munack, S.,Okvist, M.,Krengel, U. (登録日: 2015-07-15, 公開日: 2016-03-16, 最終更新日: 2024-01-10)

• 主引用文献: Munack, S.,Roderer, K.,Okvist, M.,Kamarauskaite, J.,Sasso, S.,van Eerde, A.,Kast, P.,Krengel, U.; Remote Control by Inter-Enzyme Allostery: A Novel Paradigm for Regulation of the Shikimate Pathway.; J.Mol.Biol., 428:1237-1255, 2016; PubMed: 26776476; DOI: 10.1016/j.jmb.2016.01.001

実験手法

X-RAY DIFFRACTION (2.7 Å)