5C44

Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble

Summary for 5C44

• Entry DOI: 10.2210/pdb5c44/pdb
• Related: 5C3E 5C4A 5C4J 5C4X
• Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11, ... (15 entities in total)
• Functional Keywords: protein-dna complex, rna polyermase ii, transcribing complex, transferase-dna-rna complex, transferase/dna/rna
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Cellular location: Nucleus: P04050 P38902 P08518 P16370 P20433 P20434 P34087 P20436; Nucleus, nucleolus : P22139 P40422 P27999; Cytoplasm : P20435
• Total number of polymer chains: 15
• Total formula weight: 550516.87

Authors

Barnes, C.O.,Calero, M.,Malik, I.,Spahr, H.,Zhang, Q.,Pullara, F.,Kaplan, C.D.,Calero, G. (deposition date: 2015-06-17, release date: 2015-08-26)

• Primary citation: Barnes, C.O.,Calero, M.,Malik, I.,Graham, B.W.,Spahr, H.,Lin, G.,Cohen, A.E.,Brown, I.S.,Zhang, Q.,Pullara, F.,Trakselis, M.A.,Kaplan, C.D.,Calero, G.; Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.; Mol.Cell, 59:258-269, 2015; PubMed: 26186291; DOI: 10.1016/j.molcel.2015.06.034

Experimental method

X-RAY DIFFRACTION (3.95 Å)