5C08
1E6 TCR in Complex with HLA-A0e carrying RQWGPDPAAV
Summary for 5C08
Entry DOI | 10.2210/pdb5c08/pdb |
Related | 3UTP 3UTQ 3UTS 3UTT 5C06 5C07 5C09 5C0A 5C0B 5C0C 5C0D 5C0E 5C0F 5C0G 5C0H 5C0I 5C0J 5HYJ |
Descriptor | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Marker peptide, ... (9 entities in total) |
Functional Keywords | immuno, hla-a02, 1e6-tcr, cross-reactivity, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted : P61769 |
Total number of polymer chains | 10 |
Total formula weight | 191026.31 |
Authors | Rizkallah, P.J.,Bulek, A.M.,Cole, D.K.,Sewell, A.K. (deposition date: 2015-06-12, release date: 2016-05-04, Last modification date: 2024-01-10) |
Primary citation | Cole, D.K.,Bulek, A.M.,Dolton, G.,Schauenberg, A.J.,Szomolay, B.,Rittase, W.,Trimby, A.,Jothikumar, P.,Fuller, A.,Skowera, A.,Rossjohn, J.,Zhu, C.,Miles, J.J.,Peakman, M.,Wooldridge, L.,Rizkallah, P.J.,Sewell, A.K. Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J.Clin.Invest., 126:2191-2204, 2016 Cited by PubMed: 27183389DOI: 10.1172/JCI85679 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.332 Å) |
Structure validation
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