5C01

Crystal Structure of kinase

Summary for 5C01

• Entry DOI: 10.2210/pdb5c01/pdb
• Descriptor: NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2, UNKNOWN LIGAND, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: pseudokinase domain, transferase
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 77229.35

Authors

Min, X.,Wang, Z.,Walker, N. (deposition date: 2015-06-12, release date: 2015-09-16, Last modification date: 2015-11-18)

• Primary citation: Min, X.,Ungureanu, D.,Maxwell, S.,Hammaren, H.,Thibault, S.,Hillert, E.K.,Ayres, M.,Greenfield, B.,Eksterowicz, J.,Gabel, C.,Walker, N.,Silvennoinen, O.,Wang, Z.; Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2).; J.Biol.Chem., 290:27261-27270, 2015; PubMed: 26359499; DOI: 10.1074/jbc.M115.672048

Experimental method

X-RAY DIFFRACTION (2.15 Å)