5BT2
MeCP2 MBD domain (A140V) in complex with methylated DNA
Summary for 5BT2
Entry DOI | 10.2210/pdb5bt2/pdb |
Descriptor | Methyl-CpG-binding protein 2, DNA (5'-D(*TP*CP*TP*GP*GP*AP*AP*(5CM)P*GP*GP*AP*AP*TP*TP*CP*TP*TP*CP*TP*A)-3'), DNA (5'-D(*AP*TP*AP*GP*AP*AP*GP*AP*AP*TP*TP*CP*(5CM)P*GP*TP*TP*CP*CP*AP*G)-3'), ... (4 entities in total) |
Functional Keywords | a/t run, mecp2, hydration spine, methylated dna, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 23449.56 |
Authors | |
Primary citation | Chia, J.Y.,Tan, W.S.,Ng, C.L.,Hu, N.J.,Foo, H.L.,Ho, K.L. A/T Run Geometry of B-form DNA Is Independent of Bound Methyl-CpG Binding Domain, Cytosine Methylation and Flanking Sequence. Sci Rep, 6:31210-31210, 2016 Cited by PubMed: 27502833DOI: 10.1038/srep31210 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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