5BT2
MeCP2 MBD domain (A140V) in complex with methylated DNA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Methyl-CpG-binding protein 2 | polymer | 97 | 11155.5 | 1 | UniProt (P51608) Pfam (PF01429) In PDB | Homo sapiens (Human) | MeCp2 |
2 | B | DNA (5'-D(*TP*CP*TP*GP*GP*AP*AP*(5CM)P*GP*GP*AP*AP*TP*TP*CP*TP*TP*CP*TP*A)-3') | polymer | 20 | 6138.0 | 1 | Homo sapiens | ||
3 | C | DNA (5'-D(*AP*TP*AP*GP*AP*AP*GP*AP*AP*TP*TP*CP*(5CM)P*GP*TP*TP*CP*CP*AP*G)-3') | polymer | 20 | 6156.0 | 1 | Homo sapiens | ||
4 | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence modifications
A: 77 - 167 (UniProt: P51608)
PDB | External Database | Details |
---|---|---|
Val 140 | Ala 140 | engineered mutation |
His 168 | - | expression tag |
His 169 | - | expression tag |
His 170 | - | expression tag |
His 171 | - | expression tag |
His 172 | - | expression tag |
His 173 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 23449.6 | |
All* | Total formula weight | 23449.6 |