5AJP
Crystal structure of the active form of GalNAc-T2 in complex with UDP and the glycopeptide MUC5AC-13
Summary for 5AJP
Entry DOI | 10.2210/pdb5ajp/pdb |
Related | 5AJN 5AJO |
Descriptor | POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 2, MUCIN, URIDINE-5'-DIPHOSPHATE, ... (7 entities in total) |
Functional Keywords | transferase, galnac-t2, afm, saxs, lectin domain, coarse-grained model, glycopeptides, inactive form, active form, compact form, extended form |
Biological source | HOMO SAPIENS More |
Total number of polymer chains | 2 |
Total formula weight | 69068.96 |
Authors | Lira-Navarrete, E.,delasRivas, M.,Companon, I.,Pallares, M.C.,Kong, Y.,Iglesias-Fernandez, J.,Bernardes, G.J.L.,Peregrina, J.M.,Rovira, C.,Bernado, P.,Bruscolini, P.,Clausen, H.,Lostao, A.,Corzana, F.,Hurtado-Guerrero, R. (deposition date: 2015-02-26, release date: 2015-03-11, Last modification date: 2024-01-10) |
Primary citation | Lira-Navarrete, E.,De Las Rivas, M.,Companon, I.,Pallares, M.C.,Kong, Y.,Iglesias-Fernandez, J.,Bernardes, G.J.L.,Peregrina, J.M.,Rovira, C.,Bernado, P.,Bruscolini, P.,Clausen, H.,Lostao, A.,Corzana, F.,Hurtado-Guerrero, R. Dynamic Interplay between Catalytic and Lectin Domains of Galnac-Transferases Modulates Protein O-Glycosylation. Nat.Commun., 6:6937-, 2015 Cited by PubMed: 25939779DOI: 10.1038/NCOMMS7937 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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