5AJP

Crystal structure of the active form of GalNAc-T2 in complex with UDP and the glycopeptide MUC5AC-13

Summary for 5AJP

Entry DOI	10.2210/pdb5ajp/pdb
Related	5AJN 5AJO
Descriptor	POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 2, MUCIN, URIDINE-5'-DIPHOSPHATE, ... (7 entities in total)
Functional Keywords	transferase, galnac-t2, afm, saxs, lectin domain, coarse-grained model, glycopeptides, inactive form, active form, compact form, extended form
Biological source	HOMO SAPIENS More
Total number of polymer chains	2
Total formula weight	69068.96
Authors	Lira-Navarrete, E.,delasRivas, M.,Companon, I.,Pallares, M.C.,Kong, Y.,Iglesias-Fernandez, J.,Bernardes, G.J.L.,Peregrina, J.M.,Rovira, C.,Bernado, P.,Bruscolini, P.,Clausen, H.,Lostao, A.,Corzana, F.,Hurtado-Guerrero, R. (deposition date: 2015-02-26, release date: 2015-03-11, Last modification date: 2024-01-10)
Primary citation	Lira-Navarrete, E.,De Las Rivas, M.,Companon, I.,Pallares, M.C.,Kong, Y.,Iglesias-Fernandez, J.,Bernardes, G.J.L.,Peregrina, J.M.,Rovira, C.,Bernado, P.,Bruscolini, P.,Clausen, H.,Lostao, A.,Corzana, F.,Hurtado-Guerrero, R. Dynamic Interplay between Catalytic and Lectin Domains of Galnac-Transferases Modulates Protein O-Glycosylation. Nat.Commun., 6:6937-, 2015 Cited by PubMed: 25939779 DOI: 10.1038/NCOMMS7937 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation