5A78
Crystal structure of the homing endonuclease I-CvuI in complex with I- CreI target (C1221) in the presence of 2 mM Mg revealing DNA not cleaved
Summary for 5A78
Entry DOI | 10.2210/pdb5a78/pdb |
Related | 5A72 5A73 5A74 5A75 5A77 |
Descriptor | DNA ENDONUCLEASE I-CVUI, 24MER DNA, 5'-D(*TP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP *CP*GP*AP*CP*GP*TP*TP*TP*TP*GP*A)-3', MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | hydrolase-dna complex, gene targeting, genetics, protein-dna interaction, homing endonucleases, hydrolase/dna |
Biological source | CHLORELLA VULGARIS More |
Cellular location | Plastid, chloroplast: P56347 |
Total number of polymer chains | 4 |
Total formula weight | 53371.23 |
Authors | Molina, R.,Redondo, P.,LopezMendez, B.,Villate, M.,Merino, N.,Blanco, F.J.,Valton, J.,Grizot, S.,Duchateau, P.,Prieto, J.,Montoya, G. (deposition date: 2015-07-03, release date: 2015-09-23, Last modification date: 2024-01-10) |
Primary citation | Molina, R.,Redondo, P.,Lopez-Mendez, B.,Villate, M.,Merino, N.,Blanco, F.J.,Valton, J.,Grizot, S.,Duchateau, P.,Prieto, J.,Montoya, G. Crystal Structure of the Homing Endonuclease I-Cvui Provides a New Template for Genome Modification J.Biol.Chem., 290:28727-, 2015 Cited by PubMed: 26363068DOI: 10.1074/JBC.M115.678342 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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