5A2K
Crystal structure of scFv-SM3 in complex with APD-TGalNAc-RP
Summary for 5A2K
Entry DOI | 10.2210/pdb5a2k/pdb |
Related | 5A2I 5A2J 5A2L |
Descriptor | IG LAMBDA-1 CHAIN V REGION S43, ANTIGEN TN, THR IS COVALENTLY BOUND TO GALNAC, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | immune system, glycopeptides, antibodies, molecular recognition, conformation analysis, fusion protein |
Biological source | MUS MUSCULUS (HOUSE MOUSE) More |
Total number of polymer chains | 2 |
Total formula weight | 26992.66 |
Authors | Martinez-Saez, N.,Castro-Lopez, J.,Valero-Gonzalez, J.,Madariaga, D.,Companon, I.,Somovilla, V.J.,Salvado, M.,Asensio, J.L.,Jimenez-Barbero, J.,Avenoza, A.,Busto, J.H.,Bernardes, G.J.L.,Peregrina, J.M.,Hurtado-Guerrero, R.,Corzana, F. (deposition date: 2015-05-20, release date: 2015-06-03, Last modification date: 2024-01-10) |
Primary citation | Martinez-Saez, N.,Castro-Lopez, J.,Valero-Gonzalez, J.,Madariaga, D.,Companon, I.,Somovilla, V.J.,Salvado, M.,Asensio, J.L.,Jimenez-Barbero, J.,Avenoza, A.,Busto, J.H.,Bernardes, G.J.L.,Peregrina, J.M.,Hurtado-Guerrero, R.,Corzana, F. Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an Anti-Muc1 Antibody. Angew.Chem.Int.Ed.Engl., 54:9830-, 2015 Cited by PubMed: 26118689DOI: 10.1002/ANIE.201502813 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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