5ZBQ
The Crystal Structure of human neuropeptide Y Y1 receptor with UR-MK299
Summary for 5ZBQ
Entry DOI | 10.2210/pdb5zbq/pdb |
Related | 5ZBH |
Descriptor | Neuropeptide Y receptor type 1,T4 Lysozyme, N~2~-(diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]-N~5~-(N'-{[2-(propanoylamino)ethyl]carbamoyl}carbamimidoyl)-D-ornithinamide (2 entities in total) |
Functional Keywords | g protein-coupled receptor, receptor inhibitor, complex structure, signaling protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Host cytoplasm : A0A097J792 |
Total number of polymer chains | 1 |
Total formula weight | 61210.95 |
Authors | |
Primary citation | Yang, Z.,Han, S.,Keller, M.,Kaiser, A.,Bender, B.J.,Bosse, M.,Burkert, K.,Kogler, L.M.,Wifling, D.,Bernhardt, G.,Plank, N.,Littmann, T.,Schmidt, P.,Yi, C.,Li, B.,Ye, S.,Zhang, R.,Xu, B.,Larhammar, D.,Stevens, R.C.,Huster, D.,Meiler, J.,Zhao, Q.,Beck-Sickinger, A.G.,Buschauer, A.,Wu, B. Structural basis of ligand binding modes at the neuropeptide Y Y1receptor Nature, 556:520-524, 2018 Cited by PubMed: 29670288DOI: 10.1038/s41586-018-0046-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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