5ZBQ
The Crystal Structure of human neuropeptide Y Y1 receptor with UR-MK299
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Neuropeptide Y receptor type 1,T4 Lysozyme | polymer | 525 | 60595.2 | 1 | UniProt (P25929) UniProt (A0A097J792) Pfam (PF00001) Pfam (PF00959) UniProt (by SIFTS) (P00720) | Homo sapiens (Human) | NPY1-R,Lysis protein,Lysozyme,Muramidase |
| 2 | B (A) | N~2~-(diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]-N~5~-(N'-{[2-(propanoylamino)ethyl]carbamoyl}carbamimidoyl)-D-ornithinamide | non-polymer | 615.7 | 1 | Chemie (9AO) |
Sequence modifications
A: 2 - 358 (UniProt: P25929)
A: 1001 - 1160 (UniProt: A0A097J792)
| PDB | External Database | Details |
|---|---|---|
| Trp 129 | Phe 129 | engineered mutation |
| Glu 359 | - | see sequence details |
| Phe 360 | - | see sequence details |
| Leu 361 | - | see sequence details |
| Glu 362 | - | see sequence details |
| Val 363 | - | see sequence details |
| Leu 364 | - | see sequence details |
| Phe 365 | - | see sequence details |
| Gln 366 | - | see sequence details |
| PDB | External Database | Details |
|---|---|---|
| Thr 1053 | Cys 54 | engineered mutation |
| Ala 1096 | Cys 97 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 60595.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 615.7 | |
| All* | Total formula weight | 61210.9 |
