5UDC

Crystal Structure of RSV F A2 Bound to MEDI8897

Summary for 5UDC

• Entry DOI: 10.2210/pdb5udc/pdb
• Related: 5UDD 5UDE
• Descriptor: MEDI8897 Fab Heavy Chain, MEDI8897 Fab Light Chain, Fusion glycoprotein F0, ... (5 entities in total)
• Functional Keywords: immune system, antibody, fusion glycoprotein, virus, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 9
• Total formula weight: 334058.38

Authors

McLellan, J.S. (deposition date: 2016-12-26, release date: 2017-05-17, Last modification date: 2023-10-04)

• Primary citation: Zhu, Q.,McLellan, J.S.,Kallewaard, N.L.,Ulbrandt, N.D.,Palaszynski, S.,Zhang, J.,Moldt, B.,Khan, A.,Svabek, C.,McAuliffe, J.M.,Wrapp, D.,Patel, N.K.,Cook, K.E.,Richter, B.W.M.,Ryan, P.C.,Yuan, A.Q.,Suzich, J.A.; A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants.; Sci Transl Med, 9:-, 2017; PubMed: 28469033; DOI: 10.1126/scitranslmed.aaj1928

Experimental method

X-RAY DIFFRACTION (3.45 Å)