5UDD

Crystal Structure of RSV F B9320 Bound to MEDI8897

Summary for 5UDD

Entry DOI	10.2210/pdb5udd/pdb
Related	5UDC 5UDE
Descriptor	Fusion glycoprotein F0, MEDI8897 Fab Heavy Chain, MEDI8897 Fab Light Chain, ... (4 entities in total)
Functional Keywords	immune system, antibody, fusion glycoprotein, virus, viral protein-immune system complex, viral protein/immune system
Biological source	Human Respiratory syncytial virus 9320 More
Cellular location	Host cell membrane ; Single-pass membrane protein . Virion membrane ; Single-pass type I membrane protein : Q6V2E7
Total number of polymer chains	21
Total formula weight	856995.03
Authors	McLellan, J.S. (deposition date: 2016-12-26, release date: 2017-05-17, Last modification date: 2023-10-04)
Primary citation	Zhu, Q.,McLellan, J.S.,Kallewaard, N.L.,Ulbrandt, N.D.,Palaszynski, S.,Zhang, J.,Moldt, B.,Khan, A.,Svabek, C.,McAuliffe, J.M.,Wrapp, D.,Patel, N.K.,Cook, K.E.,Richter, B.W.M.,Ryan, P.C.,Yuan, A.Q.,Suzich, J.A. A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants. Sci Transl Med, 9:-, 2017 Cited by PubMed: 28469033 DOI: 10.1126/scitranslmed.aaj1928 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.3 Å)

Structure validation